KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAPK11
All Species:
39.09
Human Site:
S252
Identified Species:
71.67
UniProt:
Q15759
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15759
NP_002742.3
364
41357
S252
E
V
L
A
K
I
S
S
E
H
A
R
T
Y
I
Chimpanzee
Pan troglodytes
Q95NE7
360
41475
S252
Y
L
I
N
R
M
P
S
H
E
A
R
N
Y
I
Rhesus Macaque
Macaca mulatta
XP_001112524
364
41320
S252
E
V
L
A
K
I
S
S
E
H
A
R
T
Y
I
Dog
Lupus familis
XP_848642
450
50049
G340
K
R
I
M
E
V
V
G
T
P
S
P
E
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9WUI1
364
41339
S252
E
V
L
A
K
I
S
S
E
H
A
R
T
Y
I
Rat
Rattus norvegicus
P70618
360
41303
S252
E
L
L
K
K
I
S
S
E
S
A
R
N
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006227
361
41762
S251
E
L
L
K
K
I
S
S
E
H
A
R
K
Y
F
Frog
Xenopus laevis
P47812
361
41700
S253
E
L
L
Q
K
I
S
S
E
A
A
R
N
Y
I
Zebra Danio
Brachydanio rerio
Q9DGE2
361
41614
S253
S
L
I
S
R
M
P
S
H
E
A
R
T
Y
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O61443
365
42080
S255
E
F
M
S
R
I
S
S
E
S
A
R
N
Y
I
Honey Bee
Apis mellifera
XP_395384
360
41360
S248
E
F
M
Q
K
I
L
S
E
S
A
R
N
Y
I
Nematode Worm
Caenorhab. elegans
Q17446
377
43900
S263
E
F
L
K
K
I
S
S
E
E
A
R
N
Y
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q96TL5
358
41225
S243
D
V
I
N
T
I
A
S
E
N
T
L
R
F
V
Conservation
Percent
Protein Identity:
100
71.4
99.7
71.5
N.A.
96.6
74.1
N.A.
N.A.
84
74.4
71.1
N.A.
65.7
67.3
59.1
N.A.
Protein Similarity:
100
85.9
99.7
74
N.A.
98
86.8
N.A.
N.A.
92
86.5
86.2
N.A.
79.1
81
73.4
N.A.
P-Site Identity:
100
33.3
100
0
N.A.
100
73.3
N.A.
N.A.
73.3
73.3
40
N.A.
60
60
73.3
N.A.
P-Site Similarity:
100
60
100
40
N.A.
100
80
N.A.
N.A.
80
80
73.3
N.A.
80
66.6
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
47.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
67.8
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
66.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
24
0
0
8
0
0
8
85
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
70
0
0
0
8
0
0
0
77
24
0
0
8
0
0
% E
% Phe:
0
24
0
0
0
0
0
0
0
0
0
0
0
8
8
% F
% Gly:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
16
31
0
0
0
0
0
% H
% Ile:
0
0
31
0
0
77
0
0
0
0
0
0
0
0
77
% I
% Lys:
8
0
0
24
62
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
39
54
0
0
0
8
0
0
0
0
8
0
0
8
% L
% Met:
0
0
16
8
0
16
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
16
0
0
0
0
0
8
0
0
47
0
0
% N
% Pro:
0
0
0
0
0
0
16
0
0
8
0
8
0
0
0
% P
% Gln:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
24
0
0
0
0
0
0
85
8
0
0
% R
% Ser:
8
0
0
16
0
0
62
93
0
24
8
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
8
0
8
0
31
0
0
% T
% Val:
0
31
0
0
0
8
8
0
0
0
0
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
0
0
0
0
0
85
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _